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Metabolic Syndrome

The Pre-Diabetes Cluster of Risk Factors

Metabolic syndrome is a cluster of conditions that often occur together: abdominal obesity, high blood pressure, elevated blood sugar, high triglycerides, and low HDL cholesterol. Having three or more of these significantly increases your risk of heart disease, stroke, and type 2 diabetes. It's essentially pre-pre-diabetes or early-stage insulin resistance—your body is struggling to manage blood sugar and insulin, but not quite badly enough yet to be diagnosed as diabetic. The root cause is typically chronic insulin resistance from years of high-carbohydrate intake. The good news? Metabolic syndrome is highly reversible through dietary changes, particularly low-carb approaches that directly address insulin resistance. An estimated 25-35% of adults in Western countries have metabolic syndrome, with some degree of insulin resistance affecting even more—making this one of our biggest public health challenges.

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  Research (2)

Dietary carbohydrate restriction as the first approach in diabetes management: Critical review and evidence base

Richard D. Feinman, Wendy K. Pogozelski, Arne Astrup, Richard K. Bernstein, Eugene J. Fine, Eric C. Westman, Anthony Accurso, Lynda Frassetto, Barbara A. Gower, Samy I. McFarlane, Jörgen Vesti Nielsen, Thure Krarup, Laura Saslow, Karl S. Roth, Mary C. Vernon, Jeff S. Volek, Gilbert B. Wilshire, Annika Dahlqvist, Ralf Sundberg, Ann Childers, Katharine Morrison, Anssi H. Manninen, Hussain M. Dashti, Richard J. Wood, Jay Wortman, Nicolai Worm

Nutrition 2015

This paper argues that restricting carbs should be the first-line diet for diabetes because it quickly lowers blood sugar, improves key health markers, and often reduces medications—without proven long‑term harms comparable to drugs.

Small Dense Low-Density Lipoprotein-Cholesterol Concentrations Predict Risk for Coronary Heart Disease

Ron C Hoogeveen, John W Gaubatz, Wensheng Sun, Rhiannon C Dodge, Jacy R Crosby, Jennifer Jiang, David Couper, Salim S Virani, Sekar Kathiresan, Eric Boerwinkle, Christie M Ballantyne

Arteriosclerosis, Thrombosis, and Vascular Biology 2014

Small, dense LDL exposes hidden heart risk: it predicts events even when LDL looks “normal.”