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5-Year effects of a novel continuous remote care model with carbohydrate-restricted nutrition therapy including nutritional ketosis in type 2 diabetes: An extension study

A L McKenzie, S J Athinarayanan, Van Tieghem MR, B M Volk, C G Roberts, R N Adams, J S Volek, S D Phinney, S J Hallberg

Diabetes research and clinical practice 2024

A 5‑year very‑low‑carb, remote‑care program for type 2 diabetes showed durable benefits: 20% remission among completers, 33% reached HbA1c <6.5% with no meds or only metformin, alongside less medication and improved heart‑risk markers.

A food-based, low-energy, low-carbohydrate diet for people with type 2 diabetes in primary care: A randomized controlled feasibility trial

Elizabeth Morris, Paul Aveyard, Pamela Dyson, Michaela Noreik, Clare Bailey, Robin Fox, Derek Jerome, Garry D Tan, Susan A Jebb

Diabetes, Obesity and Metabolism 2020

A nurse‑delivered, real‑food low‑energy, low‑carb plan led to far greater weight loss and HbA1c reductions in 12 weeks than usual care. Short‑term cardiometabolic markers and medication use improved too.

Dietary carbohydrate restriction as the first approach in diabetes management: Critical review and evidence base

Richard D. Feinman, Wendy K. Pogozelski, Arne Astrup, Richard K. Bernstein, Eugene J. Fine, Eric C. Westman, Anthony Accurso, Lynda Frassetto, Barbara A. Gower, Samy I. McFarlane, Jörgen Vesti Nielsen, Thure Krarup, Laura Saslow, Karl S. Roth, Mary C. Vernon, Jeff S. Volek, Gilbert B. Wilshire, Annika Dahlqvist, Ralf Sundberg, Ann Childers, Katharine Morrison, Anssi H. Manninen, Hussain M. Dashti, Richard J. Wood, Jay Wortman, Nicolai Worm

Nutrition 2015

This paper argues that restricting carbs should be the first-line diet for diabetes because it quickly lowers blood sugar, improves key health markers, and often reduces medications—without proven long‑term harms comparable to drugs.

Effect of a low-carbohydrate diet on appetite, blood glucose levels, and insulin resistance in obese patients with type 2 diabetes

G Boden, K Sargrad, C Homko, M Mozzoli, T P Stein

Annals of internal medicine 2005

You might wonder: Is weight loss without constant hunger even possible? Research on type 2 diabetes patients showed that a low-carb diet caused a spontaneous drop in daily calorie intake, while simultaneously boosting insulin sensitivity by 75%

Insights from a general practice service evaluation supporting a lower carbohydrate diet in patients with type 2 diabetes mellitus and prediabetes: a secondary analysis of routine clinic data including HbA1c, weight and prescribing over 6 years

David Unwin, Ali Ahsan Khalid, Jen Unwin, Dominic Crocombe, Christine Delon, Kathy Martyn, Rajna Golubic, Sumantra Ray

BMJ Nutrition, Prevention & Health 2020

Lower‑carb guidance in a UK GP practice led to 46% drug‑free type 2 diabetes remission and 93% normalization of prediabetes, with significant drops in HbA1c, weight, BP, and triglycerides.

Low Carbohydrate Dietary Approaches for People With Type 2 Diabetes—A Narrative Review

Sean D Wheatley, Trudi A Deakin, Nicola C Arjomandkhah, Paul B Hollinrake, Trudi E Reeves

Frontiers in Nutrition 2021

Low-carb diets match or beat low-fat for Type 2 diabetes—often cutting meds and improving HbA1c—without evidence of increased cardiovascular risk.

Small Dense Low-Density Lipoprotein-Cholesterol Concentrations Predict Risk for Coronary Heart Disease

Ron C Hoogeveen, John W Gaubatz, Wensheng Sun, Rhiannon C Dodge, Jacy R Crosby, Jennifer Jiang, David Couper, Salim S Virani, Sekar Kathiresan, Eric Boerwinkle, Christie M Ballantyne

Arteriosclerosis, Thrombosis, and Vascular Biology 2014

Small, dense LDL exposes hidden heart risk: it predicts events even when LDL looks “normal.”